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Natural History of ICAD
• Wong et al
1
reported one year stroke rates
705 pts with acute CVA:
– 10 % in pts with no stenotic lesion
– 17.1 % in pts with ICAD only
– 24.3 % in pts with ECAD + ICAD
– Despite medical therapy
• GESICA trial
2
symptomatic ICAD in 122
pts with a single stenosis of at least 50%
– 38.2 % pts had stroke/TIA in territory at risk
within 2 years despite medical therapy
1
Wong KS, Li H.
Stroke
2003;34:2361-6
2
.Mazighi M, Tanasescu R et al.
Neurol
2006;66:1187-91