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Fondaparinux (Arixtra)
CrCl
>80 cc/min
>50 cc/min
>30cc/min 15-29
nl
mild
moderate severe
½ life =
19 hrs
~25 hrs
~32 hrs ~ 42hrs
Clearance
100%
75%
60%
45%
50%
19 hrs
25%
38
12%
57
7% 76
Delay for surgery = 1 to 4 days