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Delay for Open Procedure
Warfarin
Dabigatran
Rivaroxiban
Coumadin
Pradaxa
Xarelto
Indicator
INR
PTT,ACT*
INR*
1/2 life (CrCl > 80 cc)
13 hrs
7 hrs
Safe wait from last dose-
CrCl > 50 cc
1 to 2 days
1 day
CrCl< 50 cc
3 to 5 days
1 day +
*
off label use
Source – package insert