Page 256 - 6107-Sentara

• Presenter name
• Title
• Date
•Subtitle of
other
information
Post Procedure Agents
Clopidigrel Prasugrel Ticagrelor ASA
PLAVIX EFFIENT BRILINTA
Load 600mg 60mg 180mg
Plt inhibition 50% 70% 90% 5-30%
Onset* 3 hr* 2 hrs** 1 hr 20 min
Permanent yes yes no yes
Site P2Y12 P2Y12 P2Y12 COX
2C19 Effect yes mild no no
* Depends on platelet inhibition assay; inhibition will increase over 24 hrs (REPAIR)
Standard protocol is 2 hrs prior to procedure
** 50% at 1 hr; 70% at 2 hrs (PI)