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IV Agents 1
Heparin
Lovenox
Angiomax
Enoxaparin Bivalrudin
Effects
AT3
AT3; Xa
Anti thrombin
Measure
ACT
~ ACT
~ ACT
½ life
chart avail
30 min
Renal Adjust
No
Yes
Ye
AT3 = antithrombin III
~ ACT = qualitative effect
Lovenox -- ~60% is mediated by AT3 and is reversible with protamine