Page 199 - 6107-Sentara

Basic HTML Version

27
Presenter name
Title
Date
Subtitle of other
information
Rheologic agents
• Trental
Pentoxifylline
and
its metabolites
improve the flow
properties of blood
by decreasing its
viscosity
• Increase blood flow
to microcirculation
• Enhanced tissue
oxygenation
• Precise mechanism
unknown
3
Pletal
Cil stazol and
metabolites are cyclic
AMP (cAMP)
phosphodiesterase III
inhibitors
suppr ss cAMP
degradation
Increase cAMP in
platelets and blood
vessels
Inhibits platelet
aggregation
Promotes vasodilatation